Diversity of bacteriophages encoding Panton-Valentine leukocidin in temporally and geographically related Staphylococcus aureus

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Panton-Valentine Leukocidin Genes in Staphylococcus aureus

To the Editor: The pathogenicity of Staphylococcus aureus depends on various bacterial surface components and extracellular proteins. However, the precise role of single virulence determinants in relation to infection is hard to establish. The frequent recovery of staphylococcal isolates that produce leukocidal toxins from patients with deep skin and soft tissue infections, particularly furuncu...

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Panton-Valentine Leukocidin–producing Staphylococcus aureus

To the Editor: Panton-Valentine leukocidin (PVL) is a cytotoxin produced by Staphylococcus aureus that causes leukocyte destruction and tissue necrosis (1). Although produced by <5% of S. aureus strains, the toxin is detected in large percentages of isolates that cause necrotic skin lesions and severe necrotizing pneumonia (2). Although commonly associated with community-acquired methicillin-re...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2020

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0228676